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ppsA [2019-04-16 12:27:48]
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ppsA [2019-04-16 12:27:48]

plipastatin synthetase
Locus
BSU18340
Isoelectric point
5.22
Molecular weight
288.86 kDa
Protein length
2561 aa Sequence Blast
Gene length
7686 bp Sequence Blast
Function
production of the antibacterial compound plipastatin
Product
plipastatin synthetase
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Miscellaneous metabolic pathways → Biosynthesis of antibacterial compounds
  • Lifestyles → Coping with stress → Biosynthesis of antibacterial compounds

    • Gene

    Coordinates
    1,990,272 → 1,997,957

    The protein

    Protein family

  • ATP-dependent AMP-binding enzyme family (according to Swiss-Prot)

    • Structure

  • 2VSQ (termination module of SrfAC, 30% identity) PubMed

    • Expression and Regulation

    Operons

    Genes
    ppsA-ppsB-ppsC-ppsD-ppsE
    Description
    PubMed

    Regulatory mechanism

  • AbrB: repression, PubMed, in AbrB regulon
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    Biological materials

    Mutant

  • BKE18340 (ΔppsA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAACGGATTCCCTCCAGTTC, downstream forward: _UP4_TAACTTTTGAAAAGGTGTGT
  • BKK18340 (ΔppsA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAACGGATTCCCTCCAGTTC, downstream forward: _UP4_TAACTTTTGAAAAGGTGTGT

    • References

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